This buffalo chicken grilled cheese is FULL of flavor and a great way to use leftover cooked chicken or rotisserie chicken. Warm, creamy, and a little spicy, this pulled chicken sandwich is easy comfort food at its finest.
Not that anyone needs a recipe for a grilled cheese sandwich, but I think this buffalo chicken grilled cheese is special enough to warrant its own post.
Reasons to Love This Recipe
- It's a grilled cheese sandwich with heft, as the chicken bumps up the protein.
- The creamy buffalo chicken mixture tastes like total comfort food - and easy comfort food, at that.
- This is a great recipe for using up a small amount of leftover cooked chicken, though it's perfectly suited for a rotisserie chicken, too.
- Chicken: Any kind of leftover cooked chicken breasts or thighs work here, but shredded a rotisserie chicken is easy if you don't have any cooked chicken on hand. You'll need about one-half cup of shredded chicken per buffalo chicken grilled cheese.
- Buffalo sauce: Use your favorite brand of buffalo/wing sauce. I'm partial to Frank's Red Hot Wings as it brings a big bite that meshes nicely with creamy sour cream and cheese.
- Cheese: Pepper jack, a nice sharp sliced cheddar, provolone, or gouda all mesh well with the zippy buffalo sauce flavors.
- Bread: Any kind of bread works (gluten-free will make this recipe gluten-free, though do check the other ingredients for hidden traces of gluten). I'm partial to multi-grain varieties or fluffy whole wheat potato bread, seen used in these pictures. Sourdough is also delicious!
- Sour cream: Since only a small amount is used in this buffalo chicken grilled cheese, any variety of sour cream or a creamy alternative, such as plain Greek yogurt or mayonnaise, will work.
- Spices: You can switch these up, though I keep things simple with garlic powder and dried basil.
First stir together all of the buffalo chicken mixture ingredients in a bowl: cooked chicken, buffalo sauce, sour cream, and spices. (The quantities pictured below are for two sandwiches.)
Now all that's left is to assemble the sandwich and cook.
- Start by placing a slice of cheese on a piece of bread. If using shredded cheese, try and get it as even of a layer as possible, stretching out to all sides.
- Next scoop on the buffalo chicken mixture and press it down into a flattened layer.
- Top with another piece of cheese.
- Then add the last piece of bread. If cooking these grilled cheeses with mayonnaise (my favorite way!), spread one-and-a-half teaspoons of it all over the top piece of bread.
While you can certainly assemble this however you like, I prefer layering the buffalo chicken mixture between the two slices of cheese and not having it right up against bread. This way the cheese melts and acts like a buffer so the sauce doesn't sog up the bread.
- If you've made slow cooker buffalo chicken, you can simply add a bit of sour cream to leftover portions to make this sandwich.
- The ingredient quantities featured in the recipe card below yield one grilled cheese sandwich. Since a rotisserie chicken will very roughly yield four cups of shredded chicken, you'll have plenty to make more grilled cheeses, or to use in other recipes. My archive of chicken recipes has many recipes to use shredded chicken if you're looking for inspiration.
- Frank's Red Hot Wings is always my choice for buffalo chicken recipes. It's thinner than other wing sauces out there and has the perfect amount of heat to it.
If you’ve enjoyed this recipe, I’d love for you to leave a star rating in the recipe card and/or a comment review below!
Buffalo Chicken Grilled Cheese
- ½ cup shredded, cooked chicken
- 1 ½ Tablespoons buffalo wing sauce or to taste
- 1 Tablespoon sour cream or plain Greek yogurt or mayonnaise
- ¼ teaspoon garlic powder
- ¼ teaspoon dried basil
- 2 slices bread your preferred variety
- 2 slices cheese your preferred variety
- Mayonnaise or butter for cooking the sandwich
- Stir together the chicken, buffalo sauce, sour cream, garlic powder, and basil in a bowl until all of the ingredients are combined.
- Place one slice of cheese onto one slice of bread. Arrange the creamy buffalo chicken mixture evenly across the slice of cheese. Top with the other slice of cheese, then the other slice of bread.
- Cook the grilled cheese in your preferred manner. Here are two options I use:Option 1: Add a small amount of butter to a pan set over medium-low heat. Place the sandwich in and cook until the bottom side reaches golden-brown. Flip and repeat for the other side, adjusting the heat and/or adding additional butter halfway through if needed.Option 2: Spread 1 ½ teaspoons of mayonnaise evenly across the entire face of one slice of bread. Cook mayo-side down in an ungreased pan over medium-low heat until the bottom side is golden brown to your liking. Spread another 1 ½ teaspoons of mayonnaise on the top side of bread before flipping the sandwich and cooking it on that side until golden-brown, as well.
- This recipe can be scaled up pretty easily. If you'd like to prep ahead, mix up the chicken mixture separately, assembling sandwiches just prior to cooking so they don't get soggy.
Nutritional information is provided as an estimate. As it can vary due to many factors (brands used, quantities, etc.), we cannot guarantee its accuracy.Food Safety and Nutrition Disclaimer
The pictures in this post were updated in May 2022 from older updates in May 2019 and May 2015. If returning to this post from a saved link, you may recognize the photo above.